James Ramsbotham, chief executive of the North East Chamber has said: “A significant number of our members are worried about the impact of leaving. The focus for us now is to ensure these business concerns are addressed. It is vital the Government ensures minimal disruption to trade and investment as the process of change begins.
“We also need to see measures to reassure businesses on issues such as access to overseas talent and the future of regional funding streams.
“We have an export record which is the strongest in the whole country and this must not be compromised as the decision to leave becomes a reality. The Government must now secure the best possible ongoing relationship with Europe and the rest of the world to enable sustained business growth in our region.”